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This portfolio reflects Lillys strategy of pursuing multiple complementary approaches to metabolic disease: Tirzepatide : Dual GIP/GLP-1 agonist (approved, injectable) Retatrutide : Triple GIP/GLP-1/glucagon agonist (Phase 3, injectable) Orforglipron : Oral GLP-1R agonist (Phase 3, oral) If retatrutide is approved, it could be positioned as a more potent option for patients requiring greater weight loss or those with MASLD, while tirzepatide and orforglipron serve other patient segments
Joint Economic Committee Congress of the United States (JEC), THE 2024 JOINT ECONOMIC REPORT
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